APPBP2 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of APPBP2 polyclonal antibody (Cat # PAB2848) in HL-60 cell line lysates (35 ug/lane). PAT1 (arrow) was detected using the purified polyclonal antibody.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of APPBP2.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to internal region of human APPBP2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of APPBP2 polyclonal antibody (Cat # PAB2848) in HL-60 cell line lysates (35 ug/lane). PAT1 (arrow) was detected using the purified polyclonal antibody. -
Gene Info — APPBP2
Entrez GeneID
10513Protein Accession#
Q92624;NP_006371Gene Name
APPBP2
Gene Alias
HS.84084, KIAA0228, PAT1
Gene Description
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
Omim ID
605324Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq
Other Designations
amyloid beta precursor protein-binding protein 2|protein interacting with APP tail 1
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Interactome
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Publication Reference
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PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein.
Zheng P, Eastman J, Vande Pol S, Pimplikar SW.
PNAS 1998 Dec; 95(25):14745.
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PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein.
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