BCHE polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant BCHE.
Immunogen
Recombinant protein corresponding to amino acids of recombinant BCHE.
Sequence
QQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry(1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human skeletal muscle with BCHE polyclonal antibody (Cat # PAB28449) shows moderate cytoplasmic positivity in myocytes at 1:50-1:200 dilution. -
Gene Info — BCHE
Entrez GeneID
590Protein Accession#
F8WEX7Gene Name
BCHE
Gene Alias
CHE1, E1
Gene Description
butyrylcholinesterase
Omim ID
177400Gene Ontology
HyperlinkGene Summary
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage. [provided by RefSeq
Other Designations
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Interactome
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Disease
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