ZBTB16 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ZBTB16.
Immunogen
Recombinant protein corresponding to amino acids of recombinant ZBTB16.
Sequence
HYTLDFLSPKTFQQILEYAYTATLQAKAEDLDDLLYAAEILEIEYLEEQCLKMLETIQASDDNDTEATMADGGAEEEEDRKARYLKNIFISKHSSEESGYASVAGQSLPGPMVDQSPSVSTSFGLSA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry(1:200-1:500)
Western Blot(1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: A-431, Lane 4: Liver, Lane 5: Tonsil with ZBTB16 polyclonal antibody (Cat # PAB28445) at 1:100-1:250 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human adrenal gland with ZBTB16 polyclonal antibody (Cat # PAB28445) shows moderate nuclear positivity in cortical cells at 1:200-1:500 dilution. -
Gene Info — ZBTB16
Entrez GeneID
7704Protein Accession#
Q05516Gene Name
ZBTB16
Gene Alias
PLZF, ZNF145
Gene Description
zinc finger and BTB domain containing 16
Omim ID
176797Gene Ontology
HyperlinkGene Summary
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq
Other Designations
Kruppel-like zinc finger protein|promyelocytic leukemia zinc finger protein|zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia)
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Interactome
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Pathway
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Disease
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