Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human small intestine with PCTK1 polyclonal antibody (Cat # PAB28420) shows moderate cytoplasmic positivity in glandular cells, with additional strong membranous positivity.
The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells. This gene is thought to escape X inactivation. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
OTTHUMP00000023208,OTTHUMP00000023209,PCTAIRE-motif protein kinase 1,serine/threonine-protein kinase