DGCR14 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant DGCR14.
Immunogen
Recombinant protein corresponding to human DGCR14.
Sequence
ASASSLLLPAASRPPRKREAGEAGAATSKQRVLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFGSALGKMSREPPPPYVTPATFETPEVHAGTGVVGNKPRPRGRGLEDGEAGEEEEKEPLPSLDV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:100-1:250)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4 °C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of HEK293T cell lysate using DGCR14 polyclonal antibody (Cat # PAB28397).
Lane 1: Negative control (vector only)
Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human heart muscle with DGCR14 polyclonal antibody (Cat # PAB28397) shows moderate nuclear positivity in myocytes. -
Gene Info — DGCR14
Entrez GeneID
8220Protein Accession#
F8WEF8Gene Name
DGCR14
Gene Alias
DGCR13, DGS-H, DGS-I, DGSH, DGSI, ES2, Es2el
Gene Description
DiGeorge syndrome critical region gene 14
Omim ID
601755Gene Ontology
HyperlinkGene Summary
This gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus. [provided by RefSeq
Other Designations
DiGeorge syndrome critical region gene 13|DiGeorge syndrome critical region gene DGSI|DiGeorge syndrome critical region protein 14|DiGeorge syndrome gene H|DiGeorge syndrome gene I|Protein DGCR13
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Interactome
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Disease
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