INTS6 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant INTS6.
Immunogen
Recombinant protein corresponding to amino acids of human INTS6.
Sequence
KYELEPSPLTQFILERKSPQTCWQVYVSNSAKYSELGHPFGYLKASTALNCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWRQSFESYLKTMPPYYLGPLKKAVRMMGAPNLIADSMEYGLSYSVISYLKKLSQQAKIES
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human hippocampus with INTS6 polyclonal antibody (Cat # PAB28389) shows strong nuclear positivity in neuronal cells at 1:50-1:200 dilution. -
Gene Info — INTS6
Entrez GeneID
26512Protein Accession#
B3KQH5Gene Name
INTS6
Gene Alias
DBI-1, DDX26, DDX26A, DICE1, DKFZp434B105, HDB, INT6, Notchl2
Gene Description
integrator complex subunit 6
Omim ID
604331Gene Ontology
HyperlinkGene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
DEAD box protein|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26|OTTHUMP00000040879|RNA helicase HDB
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