STX1A polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human brain cortex with STX1A polyclonal antibody (Cat # PAB28370). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of STX1A.
Immunogen
A synthetic peptide corresponding to 15 amino acids at N-Terminus of human STX1A.
Host
Rabbit
Reactivity
Hamster, Human, Monkey, Mouse, Pig, Rat
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except STX2 (67%).
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human brain cortex with STX1A polyclonal antibody (Cat # PAB28370). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. -
Gene Info — STX1A
Entrez GeneID
6804Protein Accession#
Q16623Gene Name
STX1A
Gene Alias
HPC-1, STX1, p35-1
Gene Description
syntaxin 1A (brain)
Omim ID
186590Gene Ontology
HyperlinkGene Summary
Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor (MIM 600565) which produces explosive exocytosis (Zhang et al., 1995 [PubMed 7622072]).[supplied by OMIM
Other Designations
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Interactome
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Pathway
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Disease
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