PDE4D polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human rectum with PDE4D polyclonal antibody ( Cat # PAB28329 ) shows strong cytoplasmic positivity in glandular cells at 1:200 - 1:500 dilution.
Immunofluorescence
Immunofluorescent staining of human cell line A-431 with PDE4D polyclonal antibody ( Cat # PAB28329 ) at 1-4 ug/mL dilution shows positivity in nuclear membrane & cytoplasm.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant PDE4D.
Immunogen
Recombinant protein corresponding to amino acids of recombinant PDE4D.
Sequence
FELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVG
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human rectum with PDE4D polyclonal antibody ( Cat # PAB28329 ) shows strong cytoplasmic positivity in glandular cells at 1:200 - 1:500 dilution.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with PDE4D polyclonal antibody ( Cat # PAB28329 ) at 1-4 ug/mL dilution shows positivity in nuclear membrane & cytoplasm. -
Gene Info — PDE4D
Entrez GeneID
5144Protein Accession#
Q08499Gene Name
PDE4D
Gene Alias
DPDE3, HSPDE4D, PDE4DN2, STRK1
Gene Description
phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins
Other Designations
cAMP-specific phosphodiesterase 4D|cAMP-specific phosphodiesterase PDE4D6|dunce-like phosphodiesterase E3|phosphodiesterase 4D, cAMP-specific (dunce
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Interactome
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Pathway
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Disease
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