SECISBP2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant SECISBP2.
Immunogen
Recombinant protein corresponding to amino acids of recombinant SECISBP2.
Sequence
SEGIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVTEQKIYTEDMAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHRNENT
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human thyroid gland with SECISBP2 polyclonal antibody ( Cat # PAB28285 ) shows strong nuclear and cytoplasmic positivity in glandular cells at 1:50 - 1:200 dilution. -
Gene Info — SECISBP2
Entrez GeneID
79048Protein Accession#
Q96T21Gene Name
SECISBP2
Gene Alias
DKFZp686C09169, SBP2
Gene Description
SECIS binding protein 2
Gene Ontology
HyperlinkGene Summary
The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. [provided by RefSeq
Other Designations
OTTHUMP00000021618|OTTHUMP00000064929|OTTHUMP00000064930|OTTHUMP00000064931|OTTHUMP00000064932|selenocysteine insertion sequence binding protein 2
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Interactome
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Disease
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