POFUT2 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human thyroid gland with POFUT2 polyclonal antibody ( Cat # PAB28284 ) shows moderate nuclear positivity in glandular cells at 1:20 - 1:50 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant POFUT2.
Immunogen
Recombinant protein corresponding to amino acids of recombinant POFUT2.
Sequence
PEGFNLRRDVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVIEYEQFIAESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCIDQLLY
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human thyroid gland with POFUT2 polyclonal antibody ( Cat # PAB28284 ) shows moderate nuclear positivity in glandular cells at 1:20 - 1:50 dilution. -
Gene Info — POFUT2
Entrez GeneID
23275Protein Accession#
Q9Y2G5Gene Name
POFUT2
Gene Alias
C21orf80, FUT13
Gene Description
protein O-fucosyltransferase 2
Omim ID
610249Gene Ontology
HyperlinkGene Summary
Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM
Other Designations
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Interactome
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Disease
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