Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human brain with PYGB polyclonal antibody (Cat # PAB28174). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq
OTTHUMP00000030488,brain glycogen phosphorylase,glycogen phosphorylase B