LOXL2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of LOXL2.
Immunogen
A synthetic peptide corresponding to 20 amino acids at internal region of human LOXL2.
Host
Rabbit
Reactivity
Bovine, Dog, Guinea pig, Horse, Human, Monkey, Mouse, Rabbit, Rat
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (15 ug/ml)
Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human prostate with LOXL2 polyclonal antibody (Cat # PAB28164). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human liver with LOXL2 polyclonal antibody (Cat # PAB28164). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. -
Gene Info — LOXL2
Entrez GeneID
4017Protein Accession#
Q9Y4K0Gene Name
LOXL2
Gene Alias
LOR2, WS9-14
Gene Description
lysyl oxidase-like 2
Omim ID
606663Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq
Other Designations
lysyl oxidase homolog 2|lysyl oxidase related 2
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Interactome
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Disease
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