HS2ST1 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with HS2ST1 polyclonal antibody (Cat # PAB28139).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with HS2ST1 polyclonal antibody (Cat # PAB28139) shows strong granular cytoplasmic positivity in exocrine glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant HS2ST1.
Immunogen
Recombinant protein corresponding to amino acids of recombinant HS2ST1.
Sequence
LRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQAKYNLINEYFLVGVTEELEDFIMLLE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with HS2ST1 polyclonal antibody (Cat # PAB28139).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with HS2ST1 polyclonal antibody (Cat # PAB28139) shows strong granular cytoplasmic positivity in exocrine glandular cells. -
Gene Info — HS2ST1
Entrez GeneID
9653Protein Accession#
Q7LGA3Gene Name
HS2ST1
Gene Alias
FLJ11317, KIAA0448, MGC131986, dJ604K5.2
Gene Description
heparan sulfate 2-O-sulfotransferase 1
Omim ID
604844Gene Ontology
HyperlinkGene Summary
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011908
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Interactome
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Pathway
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Disease
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