GSC2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant GSC2.
Immunogen
Recombinant protein corresponding to amino acids of recombinant GSC2.
Sequence
PFSIEHILSSLPERSLPARAACPPQPAGRQSPAKPEEP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with GSC2 polyclonal antibody (Cat # PAB28101) shows strong nuclear positivity in Leydig cells at 1:50-1:200 dilution. -
Gene Info — GSC2
Entrez GeneID
2928Protein Accession#
O15499Gene Name
GSC2
Gene Alias
GSCL
Gene Description
goosecoid homeobox 2
Omim ID
601845Gene Ontology
HyperlinkGene Summary
Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development. [provided by RefSeq
Other Designations
goosecoid-like
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