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Last updated: 2017/11/19

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TYMS polyclonal antibody

  • Catalog # : PAB28096
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  • Specification
  • Product Description:
  • Sheep polyclonal antibody raised against recombinant TYMS .
  • Immunogen:
  • Recombinant protein corresponding to human TYMS.
  • Host:
  • Sheep
  • Reactivity:
  • Human
  • Form:
  • Lyophilized
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Recommend Usage:
  • ELISA (1:10000 - 1:50000)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 20 mM potassium phosphate buffer, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with 0.1 mL of deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis by TYMS polyclonal antibody (Cat # PAB27950) with 4 ug of protein. Lanes 1: 1: 2000 dilution. Lane 2: 1:5000 dilution. Lane 3: 1:10000 dilution.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7298
  • Gene Name:
  • TYMS
  • Gene Alias:
  • HsT422,MGC88736,TMS,TS,TSase
  • Gene Description:
  • thymidylate synthetase
  • Gene Summary:
  • Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq
  • Other Designations:
  • Thymidylate synthase
  • Related Disease
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