WNK4 polyclonal antibody

Catalog # PAB28012

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Price

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Quantity

Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of human kidney with WNK4 polyclonal antibody ( Cat # PAB28012 ) shows strong cytoplasmic and nuclear positivity in cells in tubules at 1:20 - 1:50 dilution.

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against recombinant WNK4.

    Immunogen

    Recombinant protein corresponding to amino acids of human WNK4

    Sequence

    ISEEGKPQLVGRFQVTSSKEPAEPLPLQPTSPTLSGSPKPSTPQLTSESSDTEDSAGGGPETREALAESDRAAEGLGAGVEEEGDDGKEPQVGGSPQPLSHPSPVWMNYSYSSLCLSSEESESSGEDEEFWAEL

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Antigen affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunohistochemistry (1:20 - 1:50)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.2, (40% glycerol, 0.02% sodium azide)

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining of human kidney with WNK4 polyclonal antibody ( Cat # PAB28012 ) shows strong cytoplasmic and nuclear positivity in cells in tubules at 1:20 - 1:50 dilution.
  • Gene Info — WNK4

    Entrez GeneID

    65266

    Gene Name

    WNK4

    Gene Alias

    PHA2B, PRKWNK4

    Gene Description

    WNK lysine deficient protein kinase 4

    Omim ID

    145260 601844

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB

    Other Designations

    protein kinase, lysine deficient 4

  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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