GPX2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant GPX2.
Immunogen
Recombinant protein corresponding to amino acids of human GPX2
Sequence
VLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human urinary bladder with GPX2 polyclonal antibody ( Cat # PAB28006 ) shows strong nuclear and cytoplasmic positivity in urothelial cells. -
Gene Info — GPX2
Entrez GeneID
2877Gene Name
GPX2
Gene Alias
GI-GPx, GPRP, GSHPX-GI, GSHPx-2
Gene Description
glutathione peroxidase 2 (gastrointestinal)
Omim ID
138319Gene Ontology
HyperlinkGene Summary
This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract. [provided by RefSeq
Other Designations
gastrointestinal glutathione peroxidase 2|glutathione peroxidase 2|glutathione peroxidase-related protein 2
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Interactome
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