PPAN polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant PPAN.
Immunogen
Recombinant protein corresponding to amino acids of human PPAN.
Sequence
RWEMDRGRGRLCDQKFPKTKDKSQGAQARRGPRGASRDGG
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4 cell lysate; Lane 2: U-251MG cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human oral mucosa. -
Gene Info — PPAN
Entrez GeneID
56342Protein Accession#
Q9NQ55Gene Name
PPAN
Gene Alias
BXDC3, MGC14226, MGC45852, SSF, SSF1, SSF2
Gene Description
peter pan homolog (Drosophila)
Omim ID
607793Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. This gene was found to cotranscript with P2RY11/P2Y(11), an immediate downstream gene on the chromosome that encodes a ATP receptor. The chimeric transcripts of this gene and P2RY11 were found to be ubiquitously present and regulated during granulocytic differentiation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. [provided by RefSeq
Other Designations
homolog of S. cerevisiae SSF1|peter pan homolog|second-step splicing factor 1|suppressor of SWI4 1 homolog|suppressor of sterile four 1
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