MAPK14 (phospho T180) polyclonal antibody (Biotin)
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Specification
Product Description
Chicken polyclonal antibody against synthetic phosphopeptide of MAPK14.
Immunogen
Synthetic phosphopeptide corresponding to amino acids of MAPK14
Sequence
HTDDEM(pT)GYVATR
Host
Chicken
Reactivity
Human
Form
Liquid
Conjugation
Biotin
Purification
Antigen affinity purification
Concentration
0.2 mg/mL
Isotype
IgY
Storage Buffer
In Phosphate-Buffered Saline with 0.02% Sodium Azide.
Storage Instruction
Store at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immuno-MRM (multiple reaction monitoring)
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Gene Info — MAPK14
Entrez GeneID
1432Gene Name
MAPK14
Gene Alias
CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA
Gene Description
mitogen-activated protein kinase 14
Omim ID
600289Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
Csaids binding protein|MAP kinase Mxi2|MAX-interacting protein 2|cytokine suppressive anti-inflammatory drug binding protein|p38 MAP kinase|p38 mitogen activated protein kinase|p38alpha Exip|stress-activated protein kinase 2A
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Interactome
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Pathway
- Amyotrophic lateral sclerosis (ALS)
- Epithelial cell signaling in Helicobacter pylori infection
- Fc epsilon RI signaling pathway
- GnRH signaling pathway
- Leukocyte transendothelial migration
- MAPK signaling pathway
- Neurotrophin signaling pathway
- T cell receptor signaling pathway
- Toll-like receptor signaling pathway
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Disease
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