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MAPK14 (phospho T180) polyclonal antibody (Biotin)

  • Catalog # : PAB27981
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  • Specification
  • Product Description:
  • Chicken polyclonal antibody against synthetic phosphopeptide of MAPK14
  • Immunogen:
  • Synthetic phosphopeptide corresponding to amino acids of MAPK14
  • Sequence:
  • HTDDEM(pT)GYVATR
  • Host:
  • Chicken
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Conjugation:
  • Biotin
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.2 mg/mL
  • Isotype:
  • IgY
  • Storage Buffer:
  • In Phosphate-Buffered Saline with 0.02% Sodium Azide.
  • Storage Instruction:
  • Store at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immuno-MRM (multiple reaction monitoring)
  • Application Image
  • Immuno-MRM (multiple reaction monitoring)
  • Gene Information
  • Entrez GeneID:
  • 1432
  • Gene Name:
  • MAPK14
  • Gene Alias:
  • CSBP1,CSBP2,CSPB1,EXIP,Mxi2,PRKM14,PRKM15,RK,SAPK2A,p38,p38ALPHA
  • Gene Description:
  • mitogen-activated protein kinase 14
  • Gene Summary:
  • The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • Csaids binding protein,MAP kinase Mxi2,MAX-interacting protein 2,cytokine suppressive anti-inflammatory drug binding protein,p38 MAP kinase,p38 mitogen activated protein kinase,p38alpha Exip,stress-activated protein kinase 2A
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