CTSB polyclonal antibody (Biotin)
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Specification
Product Description
Chicken polyclonal antibody against synthetic peptide of CTSB.
Immunogen
A Synthetic peptide corresponding to amino acids of CTSB
Sequence
GQDHCGIESEVVAGIPR
Host
Chicken
Reactivity
Human
Form
Liquid
Conjugation
Biotin
Purification
Antigen affinity purification
Concentration
1 mg/mL
Isotype
IgY
Storage Buffer
In Phosphate-Buffered Saline with 0.02% Sodium Azide.
Storage Instruction
Store at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immuno-MRM (multiple reaction monitoring)
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Gene Info — CTSB
Entrez GeneID
1508Gene Name
CTSB
Gene Alias
APPS, CPSB
Gene Description
cathepsin B
Omim ID
116810Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
APP secretase|OTTHUMP00000116009|amyloid precursor protein secretase|cathepsin B1|cysteine protease|preprocathepsin B
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Interactome
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Pathway
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Disease
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