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SMG6 polyclonal antibody

  • Catalog # : PAB27944
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against recombinant SMG6.
  • Immunogen:
  • Recombinant protein corresponding to amino acids of human SMG6.
  • Sequence:
  • MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLRNKPKIKEPPGSEEFKDEIVNDRDCSAVENGTQPVKDVCKELNNQEQNGPIDP
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (1:500-1:1000)
    Immunofluorescence (1-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2, (40% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human cerebellum with SMG6 polyclonal antibody (Cat # PAB27944) shows distinct cytoplasmic and nucleolar/ nuclear positivity in Purkinje cells.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of human cell line U-2 OS with SMG6 polyclonal antibody (Cat # PAB27944) at 1-4 ug/mL dilution shows positivity in nucleus, nucleoli and cytoplasm.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • SMG6
  • Gene Alias:
  • C17orf31,EST1A,KIAA0732,SMG-6
  • Gene Description:
  • Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)
  • Gene Summary:
  • SMG6 is involved in nonsense-mediated mRNA decay (Fukuhara et al., 2005 [PubMed 15721257]).[supplied by OMIM
  • Other Designations:
  • EST1 telomerase component homolog A,Est1p-like,Smg-6 homolog, nonsense mediated mRNA decay factor,ever shorter telomeres 1A
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