OSBPL1A polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant OSBPL1A.
Immunogen
Recombinant protein corresponding to amino acids of human OSBPL1A.
Sequence
VPKNSLQQSREDWLEAIEEHSAYSTHYCSQDQLTDEEEEDTVSAADLKKSLEKAQSCQQRLDREISNFLKMIKECDMAKEMLPSFLQKVEVVSEA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2, (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum with OSBPL1A polyclonal antibody (Cat # PAB27889) shows strong cytoplasmic and nuclear positivity in Purkinje cells.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with OSBPL1A polyclonal antibody (Cat # PAB27889) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli & cytoplasm. -
Gene Info — OSBPL1A
Entrez GeneID
114876Gene Name
OSBPL1A
Gene Alias
FLJ10217, ORP-1, ORP1, OSBPL1B
Gene Description
oxysterol binding protein-like 1A
Omim ID
606730Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq
Other Designations
OSBP-related protein 1|oxysterol binding protein-like 1B|oxysterol-binding protein-like 1A|oxysterol-binding protein-related protein 1
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Interactome
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Disease
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