IFT80 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant IFT80.
Immunogen
Recombinant protein corresponding to amino acids of human IFT80.
Sequence
EELYSCSDDHQIVKWNLLTSETTQIVKLPDDIYPIDFHWFPKSLGVKKQTQAESFVLTSSDGKFHLISKLGRVEKSVEAHCGAVLAGRWNY
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with IFT80 polyclonal antibody (Cat # PAB27850) shows strong cytoplasmic positivity with a granular pattern in cells in tubules at 1:50-1:200 dilution. -
Gene Info — IFT80
Entrez GeneID
57560Gene Name
IFT80
Gene Alias
ATD2, KIAA1374, MGC126543, WDR56
Gene Description
intraflagellar transport 80 homolog (Chlamydomonas)
Gene Ontology
HyperlinkGene Summary
The IFT80 gene encodes a protein with 7 WD40 domains that is a component of the intraflagellar transport (IFT) complex B (Beales et al., 2007 [PubMed 17468754]). The IFT is essential for the development and maintenance of motile and sensory cilia.[supplied by OMIM
Other Designations
WD repeat domain 56
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Interactome
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Publication Reference
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The Effect of IFT80 Deficiency in Osteocytes on Orthodontic Loading-Induced and Physiologic Bone Remodeling: In Vivo Study.
Hyeran Helen Jeon, Jessica Kang, Jiahui Madelaine Li, Douglas Kim, Gongsheng Yuan, Nicolette Almer, Min Liu, Shuying Yang.
Life (Basel, Switzerland) 2022 Jul; 12(8):1147.
Application:IF, Human, Rabbit, Osteocytes.
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The Effect of IFT80 Deficiency in Osteocytes on Orthodontic Loading-Induced and Physiologic Bone Remodeling: In Vivo Study.
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