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ACAN polyclonal antibody

  • Catalog # : PAB27837
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ACAN.
  • Immunogen:
  • A synthetic peptide corresponding to 16 amino acid at C-terminus of human ACAN.
  • Host:
  • Rabbit
  • Reactivity:
  • Hamster, Human, Monkey, Rat
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins, except REG1A (50%).
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity chromatography
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human cartilage tissue with ACAN polyclonal antibody (Cat # PAB27837). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 176
  • Gene Name:
  • ACAN
  • Gene Alias:
  • AGC1,AGCAN,CSPG1,CSPGCP,MSK16,SEDK
  • Gene Description:
  • aggrecan
  • Gene Summary:
  • This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq
  • Other Designations:
  • aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122),aggrecan proteoglycan,cartilage-specific proteoglycan core protein,chondroitin sulfate proteoglycan 1,large aggregating proteo
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