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P2RX7 polyclonal antibody

  • Catalog # : PAB27822
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of P2RX7.
  • Immunogen:
  • A synthetic peptide corresponding to 16 amino acid at internal region of human P2RX7.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Monkey
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DDX59 (56%).
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity chromatography
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10-20 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human pancreas, nerve with P2RX7 polyclonal antibody (Cat # PAB27822). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 5027
  • Gene Name:
  • P2RX7
  • Gene Alias:
  • MGC20089,P2X7
  • Gene Description:
  • purinergic receptor P2X, ligand-gated ion channel, 7
  • Gene Summary:
  • The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq
  • Other Designations:
  • ATP receptor,P2X purinoceptor 7,P2X7 receptor,P2Z receptor,purinergic receptor P2X7
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