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SCN5A polyclonal antibody

  • Catalog # : PAB27814
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SCN5A.
  • Immunogen:
  • A synthetic peptide corresponding to 19 amino acid at internal region of human SCN5A.
  • Host:
  • Rabbit
  • Reactivity:
  • Dog, Horse, Human, Monkey, Mouse, Pig, Rat
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity chromatography
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human heart tissue with SCN5A polyclonal antibody (Cat # PAB27814). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6331
  • Gene Name:
  • SCN5A
  • Gene Alias:
  • Gene Description:
  • sodium channel, voltage-gated, type V, alpha subunit
  • Gene Summary:
  • The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • cardiac sodium channel alpha subunit,sodium channel, voltage-gated, type V, alpha (long QT syndrome 3),voltage-gated sodium channel type V alpha
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