Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human ovary tissue with NR5A1 polyclonal antibody (Cat # PAB27778). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. [provided by RefSeq