ESRRA polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human breast cancer tissue with ESRRA polyclonal antibody (Cat # PAB27776). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ESRRA.
Immunogen
A synthetic peptide corresponding to 15 amino acid at ligand-binding domain of human ESRRA.
Host
Rabbit
Reactivity
Bovine, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rat
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ESRRG (60%).
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (11-21 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human breast cancer tissue with ESRRA polyclonal antibody (Cat # PAB27776). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. -
Gene Info — ESRRA
Entrez GeneID
2101Protein Accession#
P11474Gene Name
ESRRA
Gene Alias
ERR1, ERRa, ERRalpha, ESRL1, NR3B1
Gene Description
estrogen-related receptor alpha
Omim ID
601998Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. [provided by RefSeq
Other Designations
estrogen receptor-like 1
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Interactome
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Disease
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