Product Browser

Last updated: 2017/7/16

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

NR0B2 polyclonal antibody

  • Catalog # : PAB27775
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of NR0B2.
  • Immunogen:
  • A synthetic peptide corresponding to 16 amino acid at ligand-binding domain of human NR0B2.
  • Host:
  • Rabbit
  • Reactivity:
  • Hamster, Human, Monkey, Mouse, Rabbit
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity chromatography
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human liver, hepatocytes with NR0B2 polyclonal antibody (Cat # PAB27775). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8431
  • Gene Name:
  • NR0B2
  • Gene Alias:
  • FLJ17090,SHP,SHP1
  • Gene Description:
  • nuclear receptor subfamily 0, group B, member 2
  • Gene Summary:
  • The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000004414,orphan nuclear receptor SHP,short heterodimer partner,small heterodimer partner
  • RSS
  • YouTube
  • Linkedin
  • Facebook