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CACNA1C polyclonal antibody

  • Catalog # : PAB27743
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CACNA1C.
  • Immunogen:
  • A synthetic peptide corresponding to 16 amino acid at internal region of human CACNA1C.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity chromatography
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human small intestine tissue with CACNA1C polyclonal antibody (Cat # PAB27743). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 775
  • Gene Name:
  • Gene Alias:
  • CACH2,CACN2,CACNL1A1,CCHL1A1,CaV1.2,MGC120730,TS
  • Gene Description:
  • calcium channel, voltage-dependent, L type, alpha 1C subunit
  • Gene Summary:
  • This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. [provided by RefSeq
  • Other Designations:
  • DHPR, alpha-1 subunit,calcium channel, L type, alpha 1 polypeptide, isoform 1, cardic muscle,calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit,voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*,voltage-gated c
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