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Last updated: 2017/1/15

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KCNN2 polyclonal antibody

  • Catalog # : PAB27742
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of KCNN2.
  • Immunogen:
  • A synthetic peptide corresponding to 18 amino acid at C-terminus of human KCNN2.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Monkey
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity chromatography
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human kidney tissue with KCNN2 polyclonal antibody (Cat # PAB27742). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 3781
  • Gene Name:
  • KCNN2
  • Gene Alias:
  • KCa2.2,SK2,SKCA2,hSK2
  • Gene Description:
  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • Gene Summary:
  • Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • apamin-sensitive small-conductance Ca2+-activated potassium channel,small conductance calcium-activated potassium channel protein 2
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