KCNN2 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human kidney tissue with KCNN2 polyclonal antibody (Cat # PAB27742). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of KCNN2.
Immunogen
A synthetic peptide corresponding to 18 amino acid at C-terminus of human KCNN2.
Host
Rabbit
Reactivity
Human, Monkey
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human kidney tissue with KCNN2 polyclonal antibody (Cat # PAB27742). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. -
Gene Info — KCNN2
Entrez GeneID
3781Protein Accession#
Q9H2S1Gene Name
KCNN2
Gene Alias
KCa2.2, SK2, SKCA2, hSK2
Gene Description
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
Omim ID
605879Gene Ontology
HyperlinkGene Summary
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
apamin-sensitive small-conductance Ca2+-activated potassium channel|small conductance calcium-activated potassium channel protein 2
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