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TSHR polyclonal antibody

  • Catalog # : PAB27688
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of TSHR.
  • Immunogen:
  • A synthetic peptide corresponding to 16 amino acid at N-terminus of human TSHR.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Monkey
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity chromatography
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human thyroid, follicular epithelium with TSHR polyclonal antibody (Cat # PAB27688). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 7253
  • Gene Name:
  • TSHR
  • Gene Alias:
  • CHNG1,LGR3,MGC75129,hTSHR-I
  • Gene Description:
  • thyroid stimulating hormone receptor
  • Gene Summary:
  • The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • seven transmembrane helix receptor,thyroid stimulating hormone receptor, isoform 2,thyrotropin receptor,thyrotropin receptor-I, hTSHR-I
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