CCL21 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CCL21.
Immunogen
A synthetic peptide corresponding to internal region of human CCL21.
Sequence
QGCRKDRGASKTG
Host
Goat
Theoretical MW (kDa)
16
Reactivity
Human
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:1000)
Western Blot (0.03-0.1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
CCL21 polycolnal antibody (Cat # PAB27649) (0.1 ug/mL) staining of human lymph node lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. -
Gene Info — CCL21
Entrez GeneID
6366Protein Accession#
NP_002980.1Gene Name
CCL21
Gene Alias
6Ckine, CKb9, ECL, MGC34555, SCYA21, SLC, TCA4
Gene Description
chemokine (C-C motif) ligand 21
Omim ID
602737Gene Ontology
HyperlinkGene Summary
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq
Other Designations
Efficient Chemoattractant for Lymphocytes|OTTHUMP00000000526|OTTHUMP00000000527|OTTHUMP00000021304|beta chemokine exodus-2|exodus-2|secondary lymphoid tissue chemokine|small inducible cytokine A21|small inducible cytokine subfamily A (Cys-Cys), member 21
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