OSMR polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of OSMR.
Immunogen
A synthetic peptide corresponding to internal region of human OSMR.
Sequence
QIHGEQLDPHVT
Host
Goat
Theoretical MW (kDa)
125
Reactivity
Human
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:128000)
Western Blot (0.1-0.3ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
OSMR polycolnal antibody (Cat # PAB27645) (0.1ug/ml) staining of HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. -
Gene Info — OSMR
Entrez GeneID
9180Protein Accession#
NP_003990.1Gene Name
OSMR
Gene Alias
MGC150626, MGC150627, MGC75127, OSMRB
Gene Description
oncostatin M receptor
Omim ID
601743Gene Ontology
HyperlinkGene Summary
Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF [provided by RefSeq
Other Designations
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Interactome
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