ADRA1B polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
ADRA1B polycolnal antibody (Cat # PAB27641) (0.3ug/ml) staining of human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ADRA1B.
Immunogen
A synthetic peptide corresponding to amino acids 252-264 at internal region of human ADRA1B.
Sequence
TLRIHSKNFHEDT
Host
Goat
Theoretical MW (kDa)
60
Reactivity
Chicken, Dog, Human, Mouse, Pig, Rat
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:128000)
Western Blot (0.3-1ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
ADRA1B polycolnal antibody (Cat # PAB27641) (0.3ug/ml) staining of human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. -
Gene Info — ADRA1B
Entrez GeneID
147Protein Accession#
NP_000670.1Gene Name
ADRA1B
Gene Alias
ADRA1, ALPHA1BAR
Gene Description
adrenergic, alpha-1B-, receptor
Omim ID
104220Gene Ontology
HyperlinkGene Summary
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq
Other Designations
alpha-1B-adrenergic receptor
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Interactome
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Pathway
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Disease
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