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SLC1A3 polyclonal antibody

  • Catalog # : PAB27640
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of SLC1A3.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human SLC1A3.
  • Sequence:
  • DNETEKPIDSETK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 60
  • Reactivity:
  • Human
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:8000)
    Western Blot (1-3ug/ml)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • SLC1A3 polycolnal antibody (Cat # PAB27640) (2ug/ml) staining of human hippocampus lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6507
  • Protein Accession#:
  • NP_004163.3;NP_001160167.1
  • Gene Name:
  • SLC1A3
  • Gene Alias:
  • EA6,EAAT1,FLJ25094,GLAST,GLAST1
  • Gene Description:
  • solute carrier family 1 (glial high affinity glutamate transporter), member 3
  • Gene Summary:
  • Glutamate and aspartate are excitatory neurotransmitters that have been implicated in a number of pathologic states of the nervous system. Accumulation of extracellular excitatory amino acids can be cytotoxic and may also lower the seizure threshold in epilepsy. EAAT1 (SLC1A3) is a member of a family of high-affinity sodium-dependent transporter molecules that regulate neurotransmitter concentrations at the excitatory glutamatergic synapses of the mammalian central nervous system (Kirschner et al., 1994 [PubMed 8001975]).[supplied by OMIM
  • Other Designations:
  • glutamate transporter variant EAAT1ex9skip
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