ADRA1B polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
ADRA1B polycolnal antibody (Cat # PAB27638) (0.1ug/ml) staining of human heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ADRA1B.
Immunogen
A synthetic peptide corresponding to internal region of human ADRA1B.
Sequence
SSTKAKGHNPRSS
Host
Goat
Theoretical MW (kDa)
60
Reactivity
Chicken, Dog, Human, Mouse, Pig, Rat
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:128000)
Western Blot (0.1-0.3ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
ADRA1B polycolnal antibody (Cat # PAB27638) (0.1ug/ml) staining of human heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. -
Gene Info — ADRA1B
Entrez GeneID
147Protein Accession#
NP_000670.1Gene Name
ADRA1B
Gene Alias
ADRA1, ALPHA1BAR
Gene Description
adrenergic, alpha-1B-, receptor
Omim ID
104220Gene Ontology
HyperlinkGene Summary
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq
Other Designations
alpha-1B-adrenergic receptor
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Interactome
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Pathway
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Disease
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