UROD polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of UROD.
Immunogen
A synthetic peptide corresponding to internal region of human UROD.
Sequence
KARECVGKTVTLQGN
Host
Goat
Theoretical MW (kDa)
40
Reactivity
Human
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:128000)
Western Blot (0.1-0.3ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
UROD polycolnal antibody (Cat # PAB27625) (0.1ug/ml) staining of K562 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. -
Gene Info — UROD
Entrez GeneID
7389Protein Accession#
NP_000365.3Gene Name
UROD
Gene Alias
PCT
Gene Description
uroporphyrinogen decarboxylase
Omim ID
176100Gene Ontology
HyperlinkGene Summary
This gene encodes the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria. [provided by RefSeq
Other Designations
OTTHUMP00000010502|fifth enzyme of heme biosynthetic pathway|fifth enzyme of the heme biosynthetic pathway|uroporphyrinogen III decarboxylase
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Interactome
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Pathway
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Disease
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