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TNNI3 polyclonal antibody

  • Catalog # : PAB27616
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of TNNI3.
  • Immunogen:
  • A synthetic peptide corresponding to human TNNI3.
  • Sequence:
  • ERRGEKGRALST
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 27
  • Reactivity:
  • Chicken, Dog, Human
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:128000)
    Western Blot (1-3ug/ml)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • TNNI3 polycolnal antibody (Cat # PAB27616) (1ug/ml) staining of human heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7137
  • Gene Name:
  • TNNI3
  • Gene Alias:
  • CMD2A,CMH7,MGC116817,RCM1,TNNC1,cTnI
  • Gene Description:
  • troponin I type 3 (cardiac)
  • Gene Summary:
  • Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq
  • Other Designations:
  • familial hypertrophic cardiomyopathy 7,troponin I, cardiac
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