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SGCD polyclonal antibody

  • Catalog # : PAB27590
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of SGCD.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 245-257 at internal region of human SGCD.
  • Sequence:
  • RLPHGSYTPTGTR
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 37
  • Reactivity:
  • Chicken, Dog, Human, Mouse, Pig, Rat
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:16000)
    Western Blot (0.1-0.3ug/ml)
    Immunohistochemistry (3-5ug/ml)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • SGCD polycolnal antibody (Cat # PAB27590) (0.1ug/ml) staining of human heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • SGCD polycolnal antibody (Cat # PAB27590) (3.8ug/ml) staining of paraffin embedded human skeletal muscle. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6444
  • Protein Accession#:
  • NP_000328.2;NP_758447.1;NP_001121681.1
  • Gene Name:
  • SGCD
  • Gene Alias:
  • 35DAG,CMD1L,DAGD,MGC22567,SG-delta,SGCDP,SGD
  • Gene Description:
  • sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
  • Gene Summary:
  • The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq
  • Other Designations:
  • 35kD dystrophin-associated glycoprotein,delta-sarcoglycan,dystrophin associated glycoprotein, delta sarcoglycan,placental delta sarcoglycan,sarcoglycan, delta (35kD dystrophin-associated glycoprotein)
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