TSHR polyclonal antibody
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Specifications
Product Description
Goat polyclonal antibody raised against synthetic peptide of TSHR.
Immunogen
A synthetic peptide corresponding to amino acids 101-115 at internal region of human TSHR.
Sequence
SKVTHIEIRNTRNLT
Host
Goat
Theoretical MW (kDa)
28
Reactivity
Chicken, Human
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
Western Blot (0.5-2ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
TSHR polycolnal antibody (Cat # PAB27584) (0.5ug/ml) staining of human thyroid gland lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. -
Gene Info — TSHR
Entrez GeneID
7253Protein Accession#
NP_000360.2;NP_001018046.1Gene Name
TSHR
Gene Alias
CHNG1, LGR3, MGC75129, hTSHR-I
Gene Description
thyroid stimulating hormone receptor
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
seven transmembrane helix receptor|thyroid stimulating hormone receptor, isoform 2|thyrotropin receptor|thyrotropin receptor-I, hTSHR-I
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Whole genome analyses reveal novel genes associated with chicken adaptation to tropical and frigid environments.
Shourong Shi, Dan Shao, Lingyun Yang, Qiqi Liang, Wei Han, Qian Xue, Liang Qu, Li Leng, Yishu Li, Xiaogang Zhao, Ping Dong, Muhammed Walugembe, Boniface B Kayang, Amandus P Muhairwa, Huaijun Zhou, Haibing Tong.
Journal of Advanced Research 2022 Jul; S2090-1232(22):159.
Application:WB-Ce, Chicken, Chicken liver.
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Whole genome analyses reveal novel genes associated with chicken adaptation to tropical and frigid environments.
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