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TSHR polyclonal antibody

  • Catalog # : PAB27584
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of TSHR.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 101-115 at internal region of human TSHR.
  • Sequence:
  • SKVTHIEIRNTRNLT
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 28
  • Reactivity:
  • Chicken, Human
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:16000)
    Western Blot (0.5-2ug/ml)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • TSHR polycolnal antibody (Cat # PAB27584) (0.5ug/ml) staining of human thyroid gland lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7253
  • Protein Accession#:
  • NP_000360.2;NP_001018046.1
  • Gene Name:
  • TSHR
  • Gene Alias:
  • CHNG1,LGR3,MGC75129,hTSHR-I
  • Gene Description:
  • thyroid stimulating hormone receptor
  • Gene Summary:
  • The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • seven transmembrane helix receptor,thyroid stimulating hormone receptor, isoform 2,thyrotropin receptor,thyrotropin receptor-I, hTSHR-I
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