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Last updated: 2016/12/4

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TPO polyclonal antibody

  • Catalog # : PAB27581
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of TPO.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human TPO.
  • Sequence:
  • ELRCGKHQAVGTSPQ
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 110
  • Reactivity:
  • Human
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.1-0.3ug/ml)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • TPO polycolnal antibody (Cat # PAB27581) (0.1ug/ml) staining of thyroid gland lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7173
  • Protein Accession#:
  • NP_000538.3;NP_783650.1;NP_783652.1;NP_783653.1
  • Gene Name:
  • TPO
  • Gene Alias:
  • MSA,TPX
  • Gene Description:
  • thyroid peroxidase
  • Gene Summary:
  • This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000115304,OTTHUMP00000115536,thyroid microsomal antigen,thyroperoxidase
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