NMNAT3 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of NMNAT3.
Immunogen
A synthetic peptide corresponding to amino acids 149-162 at internal region of human NMNAT3.
Sequence
QHNIHLAKEPVQNE
Host
Goat
Theoretical MW (kDa)
26
Reactivity
Dog, Human
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
Western Blot (0.1-0.3ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
NMNAT3 polycolnal antibody (Cat # PAB27576) (0.1ug/ml) staining of human kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. -
Gene Info — NMNAT3
Entrez GeneID
349565Protein Accession#
NP_835471.1; NP_001186976.1Gene Name
NMNAT3
Gene Alias
PNAT-3, PNAT3
Gene Description
nicotinamide nucleotide adenylyltransferase 3
Omim ID
608702Gene Ontology
HyperlinkGene Summary
The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]).[supplied by OMIM
Other Designations
pyridine nucleotide adenylyltransferase 3
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Pathway
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