UGT8 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of UGT8.
Immunogen
A synthetic peptide corresponding to internal region of human UGT8.
Sequence
NGKYKRNGHIK
Host
Goat
Theoretical MW (kDa)
65
Reactivity
Chicken, Dog, Human, Rat
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:64000)
Western Blot (1-3ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
MCF7 overexpressing human UGT8 and probed with UGT8 polycolnal antibody (Cat # PAB27572). Lane 1: Mock and Lane 2: overexpressing human UGT8. Primary incubation (1ug/ml) was overnight at 4°C. -
Gene Info — UGT8
Entrez GeneID
7368Protein Accession#
NP_003351.2Gene Name
UGT8
Gene Alias
CGT
Gene Description
UDP glycosyltransferase 8
Omim ID
601291Gene Ontology
HyperlinkGene Summary
Galactocerebrosides are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system and are also present in small amounts in kidney. The key enzymatic step in the biosynthesis of galactocerebrosides consists of the transfer of galactose to ceramide catalyzed by UDP-galactose ceramide galactosyltransferase (CGT, EC 2.4.1.45). The enzyme encoded by the CGT gene is the first involved in complex lipid biosynthesis in the myelinating oligodendrocyte.[supplied by OMIM
Other Designations
UDP glycosyltransferase 8 (UDP-galactose ceramide galactosyltransferase)|UDP-galactose ceramide galactosyltransferase
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