Western blot analysis of UCK2 (arrow) using UCK2 polyclonal antibody (Cat # PAB2755). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the UCK2 gene (Lane 2).
The protein encoded by this gene catalyzes the phosphorylation of uridine monophosphate to uridine diphosphate. This is the first step in the production of the pyrimidine nucleoside triphosphates required for RNA and DNA synthesis. In addition, an allele of this gene may play a role in mediating nonhumoral immunity to Hemophilus influenzae type B. [provided by RefSeq