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Last updated: 2017/3/19

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COPA polyclonal antibody

  • Catalog # : PAB27525
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of COPA.
  • Immunogen:
  • A synthetic peptide corresponding to internal region of human COPA.
  • Sequence:
  • CTRASNLENST
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 140
  • Reactivity:
  • Chicken, Human, Mouse, Pig, Rat
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:1000)
    Western Blot (0.5-2ug/ml)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • COPA polycolnal antibody (Cat # PAB27525) (0.5ug/ml) staining of human prostate lysate (35ug protein in RIPA buffer) with (Lane: 2) and without (Lane 1) blocking with the immunizing peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1314
  • Protein Accession#:
  • NP_001091868.1;NP_004362.2
  • Gene Name:
  • COPA
  • Gene Alias:
  • FLJ26320,HEP-COP
  • Gene Description:
  • coatomer protein complex, subunit alpha
  • Gene Summary:
  • In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000031846,OTTHUMP00000031847,alpha coat protein,xenin
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