IL17RA polyclonal antibody
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More Files
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Western Blot (Cell lysate)
Western blot analysis of IL17RA in A-20 cell lysate with IL17RA polyclonal antibody (Cat # PAB27447) at 1 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of IL17RA.
Immunogen
A synthetic peptide corresponding to 18 amino acids at N-terminus of human IL17RA.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
IL17RA antibody is human, mouse and rat reactive. Multiple isoforms of IL17RA are known to exist. This antibody is predicted to not cross-react with other IL-17 receptor subunits.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (2.5 ug/mL)
Immunofluorescence (20 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for up to one year.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of IL17RA in A-20 cell lysate with IL17RA polyclonal antibody (Cat # PAB27447) at 1 ug/mL.Immunohistochemistry
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
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Gene Info — IL17RA
Entrez GeneID
23765Protein Accession#
NP_055154Gene Name
IL17RA
Gene Alias
CD217, CDw217, IL-17RA, IL17R, MGC10262, hIL-17R
Gene Description
interleukin 17 receptor A
Omim ID
605461Gene Ontology
HyperlinkGene Summary
Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq
Other Designations
interleukin 17A receptor
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Interactome
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Pathway
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Disease
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