TRIM24 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TRIM24.
Immunogen
A synthetic peptide corresponding to 19 amino acids at internal region of human TRIM24.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
At least two isoforms of TRIM24 are known to exist.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
Immunocytochemistry (2.5 ug/mL)
Immunofluorescence (20 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TRIM24 in EL4 cell lysate with TRIM24 polyclonal antibody (Cat # PAB27440) at (lane 1) 0.5 and (lane 2) 1 ug/mL.Immunocytochemistry
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
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Gene Info — TRIM24
Entrez GeneID
8805Protein Accession#
NP_056989Gene Name
TRIM24
Gene Alias
PTC6, RNF82, TF1A, TIF1, TIF1A, TIF1ALPHA, hTIF1
Gene Description
tripartite motif-containing 24
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
transcriptional intermediary factor 1|transcriptional intermediary factor 1 alpha|tripartite motif protein 24
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