KREMEN2 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of KREMEN2 in HeLa cell lysate with KREMEN2 polyclonal antibody (Cat # PAB27402) at (lane 1) 1 and (lane 2) 2 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of KREMEN2.
Immunogen
A synthetic peptide corresponding to 15 amino acids at C-terminus of human KREMEN2.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
Multiple isoforms of KREMEN2 are known to exist. KREMEN2 antibody is predicted to not cross-react with other Kremen protein family members.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
Immunocytochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of KREMEN2 in HeLa cell lysate with KREMEN2 polyclonal antibody (Cat # PAB27402) at (lane 1) 1 and (lane 2) 2 ug/mL.Immunocytochemistry
Enzyme-linked Immunoabsorbent Assay
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Gene Info — KREMEN2
Entrez GeneID
79412Protein Accession#
NP_757384Gene Name
KREMEN2
Gene Alias
KRM2, MGC10791, MGC16709
Gene Description
kringle containing transmembrane protein 2
Omim ID
609899Gene Ontology
HyperlinkGene Summary
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq
Other Designations
kringle-containing transmembrane protein 2
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