IL15RA polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of IL15RA in human small intestine tissue with IL15RA polyclonal antibody (Cat # PAB27237) at (lane 1) 1 and (lane 2) 2 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of IL15RA.
Immunogen
A synthetic peptide corresponding to 16 amino acids at internal region of human IL15RA.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
Multiple isoforms of IL-15RA are known to exist.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of IL15RA in human small intestine tissue with IL15RA polyclonal antibody (Cat # PAB27237) at (lane 1) 1 and (lane 2) 2 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — IL15RA
Entrez GeneID
3601Protein Accession#
NP_001243694Gene Name
IL15RA
Gene Alias
MGC104179
Gene Description
interleukin 15 receptor, alpha
Omim ID
601070Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine receptor that specifically binds IL15 with high affinity. The receptors of IL15 and IL2 share two subunits, the IL2R beta and IL2R gamma chains. This forms the basis of many overlapping biological activities of IL15 and IL2. The IL2 receptor requires an additional IL2-specific alpha subunit for high affinity IL2 binding. This protein is structurally related to IL2R alpha, but is capable of binding IL15 with high affinity independent of other subunits, which suggests the distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported. The full length sequences of only two variants encoding distinct isoforms are available. [provided by RefSeq
Other Designations
OTTHUMP00000019021|OTTHUMP00000019022
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Interactome
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